What is the Role of Aspirin?

Epidemiological research has shown an association between the development of Reye's Syndrome and the use of aspirin (a salicylate compound) for treating the symptoms of influenza-like illnesses, chicken pox, colds, etc.

The U.S. Surgeon General, the Food and Drug Administration, the Centers for Disease Control and Prevention, and the American Academy of Pediatrics recommend that aspirin and combination products containing aspirin not be given to children under 19 years of age during episodes of fever-causing illnesses.

Acetylsalicylate is another word for aspirin; some medicine labels may use the words acetylsalicylate, acetylsalicylic acid, salicylic acid, or salicylate instead of the word aspirin. Always ask your doctor or pharmacist before taking any medication.

It is possible to develop Reye's Syndrome without taking aspirin. However, the chances of developing Reye's Syndrome can be reduced by not giving aspirin to individuals for relief of discomfort or fever without first consulting a physician for each specific use. Anti-nausea medications may also contain salicylates, and may mask the symptoms of Reye's Syndrome.

Teenagers and adults are especially at risk of developing Reye's Syndrome due to self-medication. Too often, teenagers are ingesting aspirin-type products without parental knowledge. Teenagers should be made aware of the different forms of pain relievers on the market and make certain they check with a parent before using any medications.

Aspirin or salicylate containing Medications

Epidemiologic research has shown an association between the development of Reye's Syndrome and the use of aspirin-type products for treating the symptoms of influenza-like illnesses and chicken pox. The National Reye's Syndrome Foundation, U.S. Surgeon General, the Food and Drug Administration and Centers for Disease Control and Prevention recommend that aspirin and combination products containing aspirin not be given to children or teenagers who are suffering from one of these illnesses. This listing shows products containing aspirin or salicylate compounds. THIS IS NOT A COMPLETE LIST!

Some medication labels may use the words acetylsalicylate, acetylsalicylic acid, salicylic, salicylamide, phenyl salicylates, etc., instead of the word aspirin. There is not data as to other forms of salicylate other than aspirin associated with the development of Reye's Syndrome, but until further research has answered this question, we recommend products listing these substances not be used at all in children and adolescents, because a virus may already be present before symptoms appear. Product ingredients may be reformulated periodically, so always check the label.

When in doubt ask your doctor or pharmacist.

AWARENESS- to aid in early detection and educate the public and medical communities about the risk involved with using aspirin and other salicylates.

SERVICE- to provide emotional support and guidance to families experiencing the trauma of Reye's Syndrome.

RESEARCH- to support investigation into the disease's cause, management, treatment and prevention, as well as study its impact on survivors.